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Aspergillosis is the name given to various types of diseases caused by fungi of the genus aspergillus. The most common form is allergic bronchopulmonary aspergillosis, pulmonary aspergillosis and aspergilloma incursion. Most humans inhale aspergillus spores every day, but it was usually only develops in individuals who are immunocompromised (low immune), most types of the most common aspergillus fungus attacking is aspergillus fumigatus.
Aspergillosis can occur in immunocompetent people where tissue damage that previously there had been heavy, for example, lung tissue scarring associated with tuberculosis, chronic obstructive pulmonary disease or bronchiectasis or some underlying lung disease. All animals and many plants have a very efficient mechanism to prevent themselves being infected by aspergillus, and usually only when the mechanism is damaged in some way aspergillus can grow in the body.
Risk factors for invasive aspergillosis include patients on steroids, chemotherapy treatment led to severe neutropenia, stem cell and solid organ transplantation, aids and the next stage of a genetic disease called granulomatosa of chronic diseases. Invasive aspergillosis usually occurs only in patients who are severely immune compromised and has a high mortality rate.
Invasive disease most commonly seen in the lungs, called pulmonary aspergillosis, but though less common, the spread of aspergillus to another network, including the central nervous system, sinus, bone, heart, kidneys, eyes, blood and skin, have been reported. The diagnosis can be made by the detection of aspergillus species by culture and biopsy, tissue samples under the microscope.
Chest CT scan and detection of aspergillus antigens in body fluids, by various methods, all help with diagnosis but did not give a definitive diagnosis of invasive aspergillosis. X ray tomography and calculation on the chest on the air with the sign of the crescent moon. With the invasion of hematologic patients against aspergillosis galactomannan test can be done.
There are many other drug interactions are known to itraconazole and voriconazole should be considered. For complete information about the diagnosis, treatment and prevention of aspergillosis and antifungal drugs and information about patient information leaflets please visit the support section of the patient.
The presence of fungal ball in the lungs may not cause symptoms from the outside and can be found only by a chest x-ray. The rapid invasion of Aspergillus infection in the lungs often causes cough, fever, chest pain, and difficulty breathing. If the person with a cough, then its shape, a bloody cough repeatedly and sometimes severe, even fatal, and cause a lot of bleeding.
Aspergillosis affecting the network part of the body. Other symptoms include loss feels chills, body shakes, delirious when fever, and frozen blood. Also can develop into kidney failure, liver failure (causing jaundice), and difficulty breathing.
In the case of a severe invasion of aspergillosis, therapy combination of voriconazole and caspofungin is suggested as a frontline drug for treatment. Minimize stress and overcrowding. Provide correct ventilation. Reduce contact with mold spores or nesting material is contaminated. Surgery may be required by certain local aspergillomas.
If you are not trained to do this type of work, you can get sick or cause someone in your family is sick. Aspergillus can be a serious problem, especially with people with impaired immune systems. Example, asthma, allergies, diabetes, chemical people injured, aids or HIV. There are more, but this is just an example of disorders of the immune system. If you feel that you have been exposed to these toxins and pain, contact Your doctor immediately.